HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Joel M Gottesfeld Selected Research

Friedreich Ataxia (Friedreich's Ataxia)

10/2019Molecular Mechanisms and Therapeutics for the GAA·TTC Expansion Disease Friedreich Ataxia.
1/2019Transcriptional profiling of isogenic Friedreich ataxia neurons and effect of an HDAC inhibitor on disease signatures.
1/2016Translating HDAC inhibitors in Friedreich's ataxia.
1/2015Mechanism of Action of 2-Aminobenzamide HDAC Inhibitors in Reversing Gene Silencing in Friedreich's Ataxia.
11/2014Quantitative proteomic analysis identifies targets and pathways of a 2-aminobenzamide HDAC inhibitor in Friedreich's ataxia patient iPSC-derived neural stem cells.
10/2014Epigenetic therapy for Friedreich ataxia.
8/2013Increasing frataxin gene expression with histone deacetylase inhibitors as a therapeutic approach for Friedreich's ataxia.
9/2012Rationale for the development of 2-aminobenzamide histone deacetylase inhibitors as therapeutics for Friedreich ataxia.
8/2012Role of mismatch repair enzymes in GAA·TTC triplet-repeat expansion in Friedreich ataxia induced pluripotent stem cells.
12/2011Improved Histone Deacetylase Inhibitors as Therapeutics for the Neurodegenerative Disease Friedreich's Ataxia: A New Synthetic Route.
For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown:


Joel M Gottesfeld Research Topics

Disease

20Friedreich Ataxia (Friedreich's Ataxia)
10/2019 - 08/2006
15Neurodegenerative Diseases (Neurodegenerative Disease)
01/2019 - 10/2006
6Huntington Disease (Huntington's Disease)
01/2016 - 10/2008
6Neoplasms (Cancer)
06/2012 - 07/2006
3BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
01/2010 - 01/2008
2Cardiomyopathies (Cardiomyopathy)
10/2019 - 11/2007
2Ataxia (Dyssynergia)
10/2019 - 01/2010
2Fuchs' Endothelial Dystrophy
01/2018 - 03/2015
2Myotonic Dystrophy (Dystrophia Myotonica)
03/2015 - 12/2013
2Carcinoma (Carcinomatosis)
01/2007 - 11/2004
1Muscle Weakness
10/2019
1Spinal Muscular Atrophy (Progressive Muscular Atrophy)
01/2017
1Eye Diseases (Eye Disease)
03/2015
1Neuromuscular Diseases (Neuromuscular Disease)
03/2015
1Muscular Dystrophies (Muscular Dystrophy)
12/2013
1Pancreatic Neoplasms (Pancreatic Cancer)
06/2012
1Cystic Fibrosis (Mucoviscidosis)
01/2010
1Confusion (Bewilderment)
12/2008
1Body Weight (Weight, Body)
10/2008
1Heart Diseases (Heart Disease)
04/2008
1B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
01/2008
1Hodgkin Disease (Hodgkin's Disease)
01/2008
1Genetic Translocation (Chromosomal Translocation)
01/2008
1Philadelphia Chromosome
01/2008
1Scoliosis
11/2007

Drug/Important Bio-Agent (IBA)

18Histone Deacetylase InhibitorsIBA
01/2019 - 10/2006
15FrataxinIBA
10/2019 - 08/2006
8Mitochondrial Proteins (Mitochondrial Protein)IBA
10/2019 - 04/2008
8Histone Deacetylases (Histone Deacetylase)IBA
01/2016 - 10/2006
6Histones (Histone)IBA
01/2016 - 07/2006
5Alkylating AgentsIBA
06/2012 - 11/2004
5Chlorambucil (Leukeran)FDA Link
06/2012 - 11/2004
5Nylons (Nylon)IBA
06/2012 - 11/2004
4Messenger RNA (mRNA)IBA
03/2015 - 04/2008
4DNA (Deoxyribonucleic Acid)IBA
06/2012 - 11/2004
3Proteins (Proteins, Gene)FDA Link
01/2017 - 01/2010
3EnzymesIBA
01/2016 - 12/2008
3anthranilamideIBA
01/2015 - 09/2012
2histone deacetylase 3IBA
01/2016 - 09/2009
2RNA (Ribonucleic Acid)IBA
03/2015 - 12/2013
2Biomarkers (Surrogate Marker)IBA
10/2014 - 11/2011
2HeterochromatinIBA
09/2012 - 06/2011
2PyrrolesIBA
06/2012 - 11/2004
2imidazoleIBA
06/2012 - 11/2004
1Transcription Factor 4IBA
01/2018
1Histone Acetyltransferases (Histone Acetyltransferase)IBA
01/2016
1RNA Splicing FactorsIBA
03/2015
13' Untranslated Regions (3' UTR)IBA
12/2013
1ChromatinIBA
06/2012
1polyglutamineIBA
05/2012
1Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA
01/2010
1Chloride Channels (Chloride Channel)IBA
01/2010
1BenzamidesIBA
12/2008
1Lysine (L-Lysine)FDA Link
04/2008
1compound 106IBA
04/2008
1Phosphotransferases (Kinase)IBA
01/2008
1DABAIBA
01/2007

Therapy/Procedure

11Therapeutics
10/2019 - 10/2006
2Drug Therapy (Chemotherapy)
01/2010 - 01/2008
1Oral Administration
10/2008